Ugly Betty is an Emmy winning American television comedy-drama series starring America Ferrera, Vanessa Williams, Rebecca Romijn and Eric Mabius.

The series premieres on September 28, 2006, on ABC in the United States and on CityTV in Canada. It follows the life of the unglamorous but good-natured Betty Suarez (Ferrera), and her incongruous job at the ultra-chic New York City fashion magazine "Mode". Betty's status as a "fish out of water" drives much of the plot.

The series is an adaptation of the Colombian telenovela Yo soy Betty, la fea ("I am Betty, the ugly one"), also simply known as "Betty la fea" ("Ugly Betty") written by Fernando Gaitán (also author of Café, con aroma de mujer). It is adapted into a New York City setting by creator/developer Silvio Horta and co-producers Salma Hayek and Ben Silverman, whose production companies Silent H, Ventanarosa and Reveille respectively partnered with ABC Studios (formerly Touchstone Television) to create the hour-long program for US audience. Hayek appears on the show as Sofia Reyes, in addition to playing a cameo role as an actress on a fictional telenovela watched by the main character's family in early episodes.

The show is filmed like a traditional network drama (with motion picture film), rather than the videotape production of the original series.